We would like to turn our spotlight to a wonderful couple, Ed & Marian Saltzman, who, through their generous donations, have provided invaluable help to the Bing Center. Ed Saltzman, born in 1937, attended Hofstra University where he received his BS in Bio Chemistry. He served in the US Army Medical Corps, and then 11 years at Roche Laboratories as Director of Hospital Sales. He then founded Health Learning Systems Inc., United Weight Control, and Women's Health Alliance (sold to ABC TV). He has served as vice president of the National Kidney Foundation, NYC, and the International Board at Haifa University, Israel. He and Marian (Abraham) met while attending Hofstra. They were married in 1958 and have been blessed with 3 children and 8 grandchildren.
The WM Macroglobulinemia Clinic at the DFCI is devoted to the care of patients with Waldenstrom's Macroglobulinemia and related IgM disorders, including IgM MGUS, Myeloma and Neuropathies.
For more information on the WM Clinic at DFCI, please visit the DFCI Center for Hematologic-Oncology/Waldenstrom's Macroglobulinemia Clinic.
Plasma cell regulatory pathways in WM. In recent studies, we have attempted to dissect the molecular mechanisms which prevent WM cells from fully differentiating into plasma cells. Ordinarily, B-cells mature in a defined manner passing through the mature B-cell stage to lymphoplasmacytic cells, and then onto mature plasma cells. Mature plasma cells make antibodies that serve to protect us against pathogens, and typically include the IgA and IgG antibodies.