Guang Yang, MD

Phone: 617-632-6964
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Dr. Guang Yang has joined as a research fellow with the Bing Center for Waldenstrom’s macroglobulinemia, Dana Farber Cancer Institute this past year. His education began in Beijing, China, earning him a PhD in Biochemistry and molecular biology. Dr Yang has been with the Dana Farber Cancer Institute since 2001, and with a diverse and strong background in biochemistry, molecular biology, immunology and cell biology. He is very proficient in antibody engineering, protein expression and purification, tumor antigen gene screening, RNA splicing and cell morphology research. He is a vital contributor to the Bing Center for Waldenstrom’s macroglobulinemia. Dr Yang is currently working on a variety of projects for the Bing Center for Waldenstrom’s macroglobulinemia. The following is a list of his current publications:


Guang Yang, Shu-Ching Huang, Jane Y. Wu, and Edward J. Benz, Jr. Regulated Fox-2 isoform expression mediates protein 4.1R splicing during erythroid differentiation Blood, 1 January 2008, Vol. 111, No. 1, pp. 392-401.

Yang G, Li Y, Nishimura EK, Xin H, Zhou A, Guo Y, Dong L, Denning MF, Nickoloff BJ, Cui R.. Inhibition of PAX3 by TGF-beta modulates melanocyte viability, Mol Cell, 2008, 32(4): 554-63.

Guang Yang, Shu-Ching Huang, Jane Y. Wu, and Edward J. Benz, Jr. An erythroid differentiation–specific splicing switch in protein 4.1R mediated by the interaction of SF2/ASF with an exonic splicing enhancer Blood, 1 March 2005, Vol. 105, No. 5, pp. 2146-2153

Yang G, Ran YL, Sun LX, etc. High Expression in CHO Cells and Activity of an Anti-P185(erbB2) Mouse/human Chimeric Antibody. Acta Biochemica et Biophysica Sinica, 2001, 33 (1): 87-92

Yang G, Ran YL, Sun LX, etc. Activity identification of an anti-P185erbB2 McAb C25 ad cloning of its variable region genes. Chinese Journal of Cancer, 200, 19(8): 735-738

Yang G, Yang ZH, Sun LX, etc. Preparation and identification of monoclonal antibodies against P185erbB2. Immunological Journal, 2000, 16 (2): 139-141

Yang G, Zhao JY, Xu GY, Yang PM. The quantitative study on the alteration of leukemia MDR cell line CEM/ADM in ultra structure. Progress of Anatomical Sciences, 1996, 2 (3): 260-262.

Shao SJ, Xu GY, Ling MY, Yang G. A comparison study on the ultra structure of sub-clonal cell lines with different metastatic ability. Progress of Anatomical Sciences, 1997, 3 (3): 204-207.